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Image Search Results
Journal: Journal of Clinical and Translational Hepatology
Article Title: Gasdermin D Inhibitor Necrosulfonamide Alleviates Lipopolysaccharide/D-galactosamine-induced Acute Liver Failure in Mice
doi: 10.14218/JCTH.2021.00560
Figure Lengend Snippet: Data are means±standard deviations (ALT, n=3; IL-1β and IL-18, n=5). ** p <0.01, *** p <0.001, **** p <0.0001. ALF, acute liver failure; ALT, alanine aminotransferase; D-GalN, D-galactosamine; DMSO, dimethyl sulfoxide; IL-1β, interleukin 1 beta; IL-18, interleukin 18; LPS, lipopolysaccharide; NSA, necrosulfonamide intervention group.
Article Snippet: Mice were randomly assigned to four groups using a random number table: (1) A normal control group ( n =10) with intraperitoneal injection of the same volume of saline as the ALF model modeling reagent; (2) An ALF group ( n =20) with intraperitoneal injection of LPS (Sigma-Aldrich, Saint Louis, Missouri, USA ) 50 µg/kg
Techniques: